SCHEMBL789845

SCHEMBL789845

O=S(=O)(O)c1cc(Nc2nc(NCCCO)nc(Nc3ccccc3)n2)ccc1C=Cc1ccc(Nc2nc(NCCCO)nc(Nc3ccccc3)n2)cc1S(=O)(=O)O

nearest known ligand 0.60

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 12/20 0.60
RECQL P46063 1/20 0.51
MCL1 Q07820 1/20 0.51
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
TDP1 Q9NUW8 1/20 0.44
MERTK Q12866 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8342054 1.00 KCNH3 (0.60) KCNH3RECQLMCL1CA12CA1
SCHEMBL5901846 0.99 KCNH3 (0.59) KCNH3RECQLMCL1CA12CA1
SCHEMBL1931790 0.95 KCNH3 (0.55) KCNH3RECQLMCL1CA12CA1
SCHEMBL2202442 0.94 RECQL (0.60) KCNH3RECQLMCL1CA12CA1
SCHEMBL14421440 0.94 RECQL (0.60) KCNH3RECQLMCL1CA12CA1
SCHEMBL8410526 0.93 RECQL (0.59) KCNH3RECQLMCL1CA12CA1
SCHEMBL8410553 0.93 RECQL (0.59) KCNH3RECQLMCL1CA12CA1
SCHEMBL16671697 0.93 RECQL (0.59) KCNH3RECQLMCL1CA12CA1
Potassium SCHEMBL2219951 0.93 RECQL (0.59) KCNH3RECQLMCL1CA12CA1
SCHEMBL12345437 0.92 KCNH3 (0.52) KCNH3RECQLMCL1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10808289-B2 Animal skin substrate treatment apparatus and method XEROS LIMITED (GB) 2020-10-20 US disclosed
US-10745769-B2 Method for treating a substrate made of animal fibers with solid particles and a chemical formulation XEROS LIMITED (GB) 2020-08-18 US disclosed
EP-2976453-B1 NEW CLEANING APPARATUS AND METHOD XEROS LTD (GB) 2020-05-20 EP disclosed
EP-3019585-B1 NEW CLEANING FORMULATION AND METHOD XEROS LTD (GB) 2019-09-04 EP disclosed
US-10287642-B2 Animal skin substrate treatment apparatus and method XEROS LIMITED (GB) 2019-05-14 US disclosed
EP-3066249-B1 CLEANING METHOD AND APPARATUS XEROS LTD (GB) 2019-01-09 EP disclosed
US-10081900-B2 Cleaning method including use of solid particles XEROS LIMITED (GB) 2018-09-25 US disclosed
EP-3204525-B1 ANIMAL SKIN SUBSTRATE TREATMENT APPARATUS AND METHOD XEROS LTD (GB) 2018-09-19 EP disclosed
EP-3052693-B1 CLEANING APPARATUS XEROS LTD (GB) 2018-06-06 EP disclosed
US-20180134994-A1 APPARATUS AND METHOD FOR THE TREATMENT OF A SUBSTRATE WITH OZONE BUBBLES XEROS LIMITED (GB) 2018-05-17 US disclosed
US-20120304400-A1 Cleaning Apparatus and Method XEROS LIMITED (GB) 2012-12-06 US disclosed
US-20120284931-A1 Improved Cleaning Apparatus XEROS LIMITED (GB) 2012-11-15 US disclosed
EP-2504478-A1 IMPROVED CLEANING APPARATUS Xeros Limited (GB) 2012-10-03 EP disclosed
WO-2012095677-A2 IMPROVED CLEANING METHOD XEROS LIMITED (GB) 2012-07-19 WO disclosed
WO-2012035343-A1 NOVEL CLEANING METHOD XEROS LIMITED (GB) 2012-03-22 WO disclosed
WO-2012035342-A1 POLYMER TREATMENT METHOD XEROS LIMITED (GB) 2012-03-22 WO disclosed
WO-2011128680-A2 METHOD TO CLEAN A MOISTENED SOILED SUBSTRATE WITH POLYMERIC PARTICLES XEROS LIMITED (GB) 2011-10-20 WO disclosed
WO-2011098815-A1 IMPROVED CLEANING APPARATUS AND METHOD XEROS LIMITED (GB) 2011-08-18 WO disclosed
WO-2011064581-A1 IMPROVED CLEANING APPARATUS XEROS LIMITED (GB) 2011-06-03 WO disclosed
WO-1999013841-A1 HAIR STYLING COMPOSITIONS COMPRISING NONIONIC AND AMPHOTERIC OPTICAL BRIGHTENERS THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed