Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 11/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806962 | 0.91 | PI4KA (0.62) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL791172 | 0.90 | PI4KA (0.68) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL796868 | 0.88 | PIK3CG (0.60) | PI4KAPIK3CGPIK3CAPIK3CD | |
| SCHEMBL790028 | 0.88 | PI4KA (0.60) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL790426 | 0.87 | PI4KA (0.58) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL790402 | 0.87 | PI4KA (0.58) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL790926 | 0.87 | PI4KA (0.58) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL790186 | 0.85 | PI4KA (0.53) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL791544 | 0.85 | PI4KA (0.64) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL807197 | 0.85 | PIK3CG (0.59) | PI4KAPIK3CGPIK3CARIPK2MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |