Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 8/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.46 |
| ▸ | MTOR | P42345 | 3/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.44 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807092 | 0.90 | PI4KA (0.55) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL790102 | 0.88 | PIK3CG (0.66) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL790869 | 0.86 | PI4KA (0.62) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL790763 | 0.86 | PIK3CG (0.62) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL789858 | 0.85 | PI4KA (0.59) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL10277973 | 0.85 | PI4KA (0.49) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL789337 | 0.81 | PIK3CG (0.77) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL790388 | 0.79 | PIK3CG (0.56) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL790832 | 0.79 | PIK3CG (0.51) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL789512 | 0.76 | KEAP1 (0.55) | ABCB1ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |