Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.69 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.69 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.69 |
| ▸ | TERT | O14746 | 6/20 | 0.61 |
| ▸ | PTPRC | P08575 | 4/20 | 0.57 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7162862 | 0.86 | GRIN1 (0.69) | GRIN1GRIN2AGRIN2BTERTPTPRC | |
| SCHEMBL7160373 | 0.86 | GRIN1 (0.69) | GRIN1GRIN2AGRIN2BTERTPTPRC | |
| SCHEMBL7160424 | 0.86 | GRIN1 (0.68) | GRIN1GRIN2AGRIN2BTERTPTPRC | |
| SCHEMBL14527855 | 0.85 | GRIN1 (0.67) | GRIN1GRIN2AGRIN2BTERTPTPRC | |
| SCHEMBL13875721 | 0.84 | GRIN1 (0.67) | GRIN1GRIN2AGRIN2BTERTPTPRC | |
| SCHEMBL5173579 | 0.84 | GRIN1 (0.66) | GRIN1GRIN2AGRIN2BTERTPTPRC | |
| SCHEMBL5175136 | 0.84 | GRIN1 (0.66) | GRIN1GRIN2AGRIN2BTERTPTPRC | |
| Hydrochloric Acid SCHEMBL8203515 | 0.83 | GRIN1 (0.85) | GRIN1GRIN2AGRIN2BTERTPTPRC | |
| SCHEMBL7897660 | 0.83 | TERT (0.64) | GRIN1GRIN2AGRIN2BTERTPTPRC | |
| SCHEMBL20989432 | 0.83 | GRIN1 (0.65) | GRIN1GRIN2AGRIN2BTERTPTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191273-B1 | 3,6,10,14-SUBSTITUTED-3,6,10,16-TETRAAZABICYCLO(10.3.1)-HEXADE CA-1(16),12,14-TRIENE COMPOUNDS OF GIVEN FORMULA; ANTIBACTERIAL AND OTHER UTILITIES, SUCH AS TO SCREEN FOR PESTICIDES OR DRUGS | ISIS PHARMACEUTICALS, INC. | 2001-02-20 | — | — | US | claimed |
| WO-1999011612-A2 | SUBSTITUTED CYCLIC COMPOUNDS AND MIXTURES COMPRISING SAME | ISIS PHARMACEUTICALS, INC. (US) | 1999-03-11 | — | — | WO | claimed |
| US-6191273-B1 | 3,6,10,14-SUBSTITUTED-3,6,10,16-TETRAAZABICYCLO(10.3.1)-HEXADE CA-1(16),12,14-TRIENE COMPOUNDS OF GIVEN FORMULA; ANTIBACTERIAL AND OTHER UTILITIES, SUCH AS TO SCREEN FOR PESTICIDES OR DRUGS | ISIS PHARMACEUTICALS, INC. | 2001-02-20 | — | — | US | disclosed |
| WO-1999011612-A2 | SUBSTITUTED CYCLIC COMPOUNDS AND MIXTURES COMPRISING SAME | ISIS PHARMACEUTICALS, INC. (US) | 1999-03-11 | — | — | WO | disclosed |