Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 14/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.38 |
| ▸ | ITGAV | P06756 | 7/20 | 0.38 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.38 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.38 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900088 | 0.87 | HPGD (0.46) | GAATAS1R3TAS1R1ITGB3ITGA2B | |
| SCHEMBL7900081 | 0.86 | GAA (0.41) | GAATAS1R3TAS1R1ITGB3ITGA2B | |
| SCHEMBL7900087 | 0.85 | GAA (0.41) | GAATAS1R3TAS1R1ITGB3ITGA2B | |
| SCHEMBL4702523 | 0.84 | GAA (0.48) | GAATAS1R3TAS1R1ITGB3ITGA2B | |
| SCHEMBL7904023 | 0.83 | GAA (0.42) | GAATAS1R3TAS1R1ITGB3ITGA2B | |
| SCHEMBL7892878 | 0.83 | FOLH1 (0.47) | GAATAS1R3TAS1R1ITGB3ITGA2B | |
| SCHEMBL7898913 | 0.83 | GAA (0.42) | GAATAS1R3TAS1R1ITGB3ITGA2B | |
| SCHEMBL7898800 | 0.83 | GAA (0.41) | GAATAS1R3TAS1R1ITGB3ITGA2B | |
| SCHEMBL7901816 | 0.83 | POLB (0.45) | GAATAS1R3TAS1R1ITGB3ITGA2B | |
| SCHEMBL7902069 | 0.83 | GAA (0.41) | GAATAS1R3TAS1R1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194448-B1 | ANTIINFLAMMATORY AGENTS; ASTHMA; RHEUMATIC DISORDERS | TEXAS BIOTECHNOLOGY CORPORATION | 2001-02-27 | — | — | US | disclosed |