Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.39 |
| ▸ | ITGAV | P06756 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6127212 | 0.93 | POLB (0.46) | POLBHPGDGAATAS1R3TAS1R1 | |
| SCHEMBL20530282 | 0.93 | POLB (0.46) | POLBHPGDGAATAS1R3TAS1R1 | |
| SCHEMBL6127110 | 0.93 | POLB (0.46) | POLBHPGDGAATAS1R3TAS1R1 | |
| SCHEMBL6122200 | 0.93 | POLB (0.46) | POLBHPGDGAATAS1R3TAS1R1 | |
| SCHEMBL17009347 | 0.93 | POLB (0.46) | POLBHPGDGAATAS1R3TAS1R1 | |
| SCHEMBL4698443 | 0.93 | POLB (0.46) | POLBHPGDGAATAS1R3TAS1R1 | |
| SCHEMBL7900077 | 0.91 | HPGD (0.44) | POLBHPGDGAATAS1R3TAS1R1 | |
| SCHEMBL4700500 | 0.89 | POLB (0.43) | POLBHPGDGAATAS1R3TAS1R1 | |
| SCHEMBL7900088 | 0.89 | HPGD (0.46) | HPGDGAATAS1R3TAS1R1KMT2A | |
| SCHEMBL7900215 | 0.88 | KMT2A (0.39) | POLBGAATAS1R3TAS1R1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194448-B1 | ANTIINFLAMMATORY AGENTS; ASTHMA; RHEUMATIC DISORDERS | TEXAS BIOTECHNOLOGY CORPORATION | 2001-02-27 | — | — | US | claimed |
| US-6194448-B1 | ANTIINFLAMMATORY AGENTS; ASTHMA; RHEUMATIC DISORDERS | TEXAS BIOTECHNOLOGY CORPORATION | 2001-02-27 | — | — | US | disclosed |