Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.50 |
| ▸ | F13A1 | P00488 | 4/20 | 0.50 |
| ▸ | TGM1 | P22735 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31690564 | 0.91 | ALDH1A1 (0.51) | NPY5RALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL4371394 | 0.91 | ALDH1A1 (0.51) | NPY5RALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL25352345 | 0.90 | F13A1 (0.52) | NPY5RF13A1TGM1ALDH1A1MEN1 | |
| SCHEMBL1025858 | 0.86 | ALDH1A1 (0.48) | NPY5RALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL3819686 | 0.84 | KMT2A (0.48) | NPY5RF13A1TGM1ALDH1A1MEN1 | |
| SCHEMBL30517727 | 0.84 | F13A1 (0.48) | NPY5RF13A1TGM1ALDH1A1MEN1 | |
| SCHEMBL3517984 | 0.84 | ALDH1A1 (0.50) | NPY5RF13A1TGM1ALDH1A1MEN1 | |
| SCHEMBL1024656 | 0.83 | ALDH1A1 (0.49) | NPY5RALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL7898674 | 0.83 | NPY5R (0.59) | NPY5RF13A1TGM1ALDH1A1MEN1 | |
| SCHEMBL14163378 | 0.82 | NPY5R (0.52) | NPY5RF13A1TGM1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191273-B1 | 3,6,10,14-SUBSTITUTED-3,6,10,16-TETRAAZABICYCLO(10.3.1)-HEXADE CA-1(16),12,14-TRIENE COMPOUNDS OF GIVEN FORMULA; ANTIBACTERIAL AND OTHER UTILITIES, SUCH AS TO SCREEN FOR PESTICIDES OR DRUGS | ISIS PHARMACEUTICALS, INC. | 2001-02-20 | — | — | US | disclosed |