Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3707269 | 1.00 | SLC6A9 (0.37) | SLC6A9TSHRMAPTHSD17B10ITGB3 | |
| SCHEMBL7896578 | 0.89 | SLC6A9 (0.36) | SLC6A9 | |
| SCHEMBL3708353 | 0.89 | SLC6A9 (0.36) | SLC6A9 | |
| SCHEMBL4177209 | 0.88 | SLC6A9 (0.36) | SLC6A9 | |
| SCHEMBL3707332 | 0.88 | SLC6A9 (0.36) | SLC6A9 | |
| SCHEMBL4177205 | 0.88 | SLC6A9 (0.36) | SLC6A9 | |
| SCHEMBL3789660 | 0.78 | HTR2A (0.32) | ALDH1A1 | |
| SCHEMBL3789656 | 0.78 | HTR2A (0.32) | ALDH1A1 | |
| SCHEMBL3707190 | 0.77 | TSHR (0.41) | SLC6A9TSHRMAPTHSD17B10KDM4E | |
| SCHEMBL7899351 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087761-A1 | 2-AZA-BICYCLO[2.2.2]OCTANE COMPOUNDS AND USES THEREOF | ASTRAZENECA AB (SE) | 2010-08-05 | — | — | WO | disclosed |