Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.64 |
| ▸ | CNR2 | P34972 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13807807 | 0.91 | CNR1 (0.77) | CNR1CNR2POLBTP53LMNA | |
| SCHEMBL7897125 | 0.91 | CNR1 (0.64) | CNR1CNR2DRD2POLBLMNA | |
| SCHEMBL7905749 | 0.88 | CNR1 (0.61) | CNR1CNR2DRD2POLBTP53 | |
| SCHEMBL7897129 | 0.88 | CNR1 (0.60) | CNR1CNR2DRD2POLBTP53 | |
| SCHEMBL7896379 | 0.85 | TP53 (0.64) | CNR1CNR2DRD2POLBTP53 | |
| SCHEMBL5057259 | 0.84 | CNR1 (0.83) | CNR1CNR2POLBTP53LMNA | |
| SCHEMBL7904011 | 0.84 | DRD2 (0.64) | CNR1CNR2DRD2POLBTP53 | |
| SCHEMBL7902959 | 0.84 | CNR1 (0.58) | CNR1CNR2DRD2POLBTP53 | |
| SCHEMBL7897128 | 0.83 | TP53 (0.66) | CNR1CNR2DRD2POLBTP53 | |
| SCHEMBL7897794 | 0.82 | CNR1 (0.61) | CNR1CNR2DRD2TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010062565-A1 | MUSCARINIC AGONISTS | ACADIA PHARMACEUTICALS INC. (US) | 2010-06-03 | — | — | WO | disclosed |