Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 16/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13097089 | 0.92 | SLC6A9 (0.54) | SLC6A9SMN1; SMN2TSHRNQO2MTNR1A | |
| Hydrochloric Acid SCHEMBL3111910 | 0.91 | SLC6A9 (0.53) | SLC6A9SMN1; SMN2TSHRNQO2MTNR1A | |
| SCHEMBL3107943 | 0.89 | SLC6A9 (0.47) | SLC6A9SMN1; SMN2TSHRNQO2MTNR1A | |
| SCHEMBL3100798 | 0.89 | SLC6A9 (0.55) | SLC6A9SMN1; SMN2TSHRNQO2MTNR1A | |
| SCHEMBL7895349 | 0.88 | SLC6A9 (0.70) | SLC6A9KCNH2 | |
| SCHEMBL3100135 | 0.86 | SLC6A9 (0.51) | SLC6A9SMN1; SMN2TSHRNQO2MTNR1A | |
| SCHEMBL3101374 | 0.86 | SLC6A9 (0.73) | SLC6A9KCNH2 | |
| SCHEMBL3097675 | 0.85 | SMN1; SMN2 (0.45) | SLC6A9SMN1; SMN2TSHRNQO2MTNR1A | |
| SCHEMBL7893902 | 0.85 | SLC6A9 (0.71) | SLC6A9KCNH2 | |
| SCHEMBL3100875 | 0.84 | SLC6A9 (0.66) | SLC6A9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010092180-A1 | Aminotetraline derivatives, pharmaceutical compositions containing them, and their use in therapy | ABBOTT GMBH & CO. KG (DE) | 2010-08-19 | — | — | WO | disclosed |