Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 7/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.47 |
| ▸ | MTOR | P42345 | 3/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807320 | 0.88 | PIK3CG (0.72) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL806968 | 0.82 | PIK3CG (0.72) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL10277754 | 0.81 | PIK3CG (0.71) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL807470 | 0.81 | PIK3CG (0.55) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL791064 | 0.81 | PIK3CG (0.81) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL807455 | 0.80 | PI4KA (0.55) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL807244 | 0.78 | PIK3CG (0.61) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL807175 | 0.78 | PIK3CG (0.76) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL790765 | 0.77 | PIK3CG (0.74) | PI4KAPIK3CGPIK3CDPIK3CAMTOR | |
| SCHEMBL807256 | 0.76 | PIK3CG (0.87) | PI4KAPIK3CGPIK3CDPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |