Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.55 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.55 |
| ▸ | RXRA | P19793 | 7/20 | 0.53 |
| ▸ | RXRB | P28702 | 7/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3739645 | 0.92 | HSD17B1 (0.50) | HSD17B1HSD17B2RXRARXRBBCL2 | |
| SCHEMBL15240684 | 0.92 | HSD17B1 (0.50) | HSD17B1HSD17B2RXRARXRBBCL2 | |
| SCHEMBL13197684 | 0.85 | HSD17B1 (0.45) | HSD17B1HSD17B2POLBMAPTCTDSP1 | |
| SCHEMBL36913 | 0.85 | HSD17B1 (0.45) | HSD17B1HSD17B2POLBMAPTCTDSP1 | |
| SCHEMBL1107803 | 0.85 | HSD17B1 (0.45) | HSD17B1HSD17B2POLBMAPTCTDSP1 | |
| SCHEMBL2929456 | 0.85 | HSD17B1 (0.45) | HSD17B1HSD17B2POLBMAPTCTDSP1 | |
| SCHEMBL3443345 | 0.85 | HSD17B1 (0.45) | HSD17B1HSD17B2POLBMAPTCTDSP1 | |
| SCHEMBL5143671 | 0.85 | HSD17B1 (0.45) | HSD17B1HSD17B2POLBMAPTCTDSP1 | |
| SCHEMBL21922635 | 0.85 | HSD17B1 (0.45) | HSD17B1HSD17B2POLBMAPTCTDSP1 | |
| SCHEMBL22356719 | 0.85 | HSD17B1 (0.45) | HSD17B1HSD17B2POLBMAPTCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284365-B1 | FOR CONTROLLING PHYSICAL PROPERTIES OF SURFACE AND INTERFACE OF SOLID ARTICLE SUCH AS WETTABILITY, ADHESIVE PROPERTY, SURFACE ENERGY, DISPERSABILITY, CHEMICAL RESISTANCE | FUJI XEROX CO., LTD. (JP) | 2001-09-04 | — | — | US | disclosed |