Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 9/20 | 0.49 |
| ▸ | PI4KA | P42356 | 6/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.45 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806785 | 0.88 | PIK3CG (0.49) | PIK3CGPI4KAPIK3CDPIK3CAPIK3CB | |
| SCHEMBL807136 | 0.80 | PIK3CG (0.73) | PIK3CGPI4KAPIK3CDPIK3CAPIK3CB | |
| SCHEMBL14317941 | 0.75 | PIK3CG (0.67) | PIK3CGPI4KAPIK3CDPIK3CAPIK3CB | |
| SCHEMBL3114056 | 0.74 | PIK3CG (0.64) | PIK3CGPI4KAPIK3CDPIK3CAPIK3CB | |
| SCHEMBL807046 | 0.74 | PIK3CG (0.44) | PIK3CGPI4KAPIK3CDPIK3CAMTOR | |
| Formic Acid SCHEMBL14247639 | 0.73 | PI4KA (0.63) | PIK3CGPI4KAPIK3CDPIK3CAMTOR | |
| SCHEMBL807470 | 0.73 | PIK3CG (0.55) | PIK3CGPI4KAPIK3CDPIK3CAMTOR | |
| SCHEMBL10277708 | 0.70 | PI4KA (0.51) | PIK3CGPI4KAPIK3CDPIK3CAPIK3CB | |
| SCHEMBL10277681 | 0.70 | LRRK2 (0.47) | — | |
| SCHEMBL14247315 | 0.69 | PI4KA (0.67) | PIK3CGPI4KAPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |