Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 5/20 | 0.44 |
| ▸ | PI4KA | P42356 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKLR | P30613 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790228 | 0.93 | PI4KA (0.52) | PIK3CGPI4KAALDH1A1PIK3CAMTOR | |
| SCHEMBL798151 | 0.86 | PIK3CG (0.56) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL807470 | 0.84 | PIK3CG (0.55) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL10274897 | 0.81 | PIK3CG (0.54) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL791568 | 0.80 | PI4KA (0.43) | PIK3CGPI4KATP53HSD17B10ALDH1A1 | |
| SCHEMBL789741 | 0.79 | PI4KA (0.46) | PIK3CGPI4KATP53HSD17B10ALDH1A1 | |
| SCHEMBL790802 | 0.79 | PIK3CG (0.64) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL807247 | 0.77 | PIK3CG (0.48) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL790751 | 0.77 | PIK3CA (0.58) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL790545 | 0.77 | PIK3C3 (0.44) | PIK3CGPI4KATP53HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |