Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 6/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7897104 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3EPHX2 | |
| SCHEMBL7901914 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3EPHX2 | |
| SCHEMBL7901864 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3EPHX2 | |
| SCHEMBL7890341 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3EPHX2 | |
| SCHEMBL7890286 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3EPHX2 | |
| SCHEMBL7890288 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3EPHX2 | |
| SCHEMBL7890281 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3EPHX2 | |
| SCHEMBL7901780 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3EPHX2 | |
| SCHEMBL7900150 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3EPHX2 | |
| SCHEMBL7897224 | 1.00 | DGKA (0.62) | DGKAPRSS1PRSS2PRSS3EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187938-B1 | TRANSDERMAL PENETRATION ENHANCERS | BOCHEMIE, S.R.O. (CZ) | 2001-02-13 | — | — | US | disclosed |
| EP-0973710-A2 | OMEGA-AMINO ACID DERIVATIVES, PROCESSES OF THEIR PREPARATION AND THEIR USE | Bochemie S.R.O. (CZ) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998045233-A2 | OMEGA-AMINO ACID DERIVATIVES, PROCESSES OF THEIR PREPARATION AND THEIR USE | BOCHEMIE S.R.O. (CZ) | 1998-10-15 | — | — | WO | disclosed |