Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 16/20 | 0.68 |
| ▸ | SSTR5 | P35346 | 13/20 | 0.68 |
| ▸ | SSTR1 | P30872 | 12/20 | 0.68 |
| ▸ | SSTR2 | P30874 | 12/20 | 0.68 |
| ▸ | SSTR3 | P32745 | 12/20 | 0.68 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.49 |
| ▸ | TACR1 | P25103 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900195 | 1.00 | SSTR4 (0.68) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL7903366 | 0.83 | SSTR4 (0.49) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL7903368 | 0.83 | SSTR4 (0.49) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL7900270 | 0.82 | SSTR5 (0.45) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL7894559 | 0.81 | SSTR4 (1.00) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL7894557 | 0.81 | SSTR4 (1.00) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL7900265 | 0.78 | PDE4D (0.43) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL8432093 | 0.75 | SSTR1 (0.51) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL8432094 | 0.75 | SSTR1 (0.51) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL8331943 | 0.75 | SSTR1 (0.46) | SSTR4SSTR5SSTR1SSTR2SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197963-B1 | TETRAHYDROPYRAN DERIVATIVES; PROTEIN G, SOMATOSTATIN, AND NATURAL KILLER CELL RECEPTOR ANTAGONISTS OR MIMETICS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2001-03-06 | — | — | US | disclosed |
| US-5811512-A | BINDING TO G-PROTEIN-LINKED RECEPTORS, SUBSTANCE P RECEPTOR; HORMONE INHIBITORS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-09-22 | — | — | US | disclosed |
| US-5552534-A | COMPOUNDS FOR CROSS REACTION WITH PEPTIDES FOR BINDING G PROTEIN | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1996-09-03 | — | — | US | disclosed |