Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 3/20 | 0.45 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.45 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.45 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.40 |
| ▸ | GJB2 | P29033 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900265 | 0.87 | PDE4D (0.43) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL8331943 | 0.84 | SSTR1 (0.46) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7900294 | 0.82 | SSTR1 (0.40) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7900201 | 0.82 | SSTR4 (0.68) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7900195 | 0.82 | SSTR4 (0.68) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7900290 | 0.82 | SSTR1 (0.40) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL19400304 | 0.78 | GJB2 (0.54) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL8432093 | 0.77 | SSTR1 (0.51) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL8432094 | 0.77 | SSTR1 (0.51) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL6879922 | 0.77 | SSTR5 (0.65) | SSTR5SSTR1SSTR2SSTR4SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197963-B1 | TETRAHYDROPYRAN DERIVATIVES; PROTEIN G, SOMATOSTATIN, AND NATURAL KILLER CELL RECEPTOR ANTAGONISTS OR MIMETICS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2001-03-06 | — | — | US | disclosed |
| US-5811512-A | BINDING TO G-PROTEIN-LINKED RECEPTORS, SUBSTANCE P RECEPTOR; HORMONE INHIBITORS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-09-22 | — | — | US | disclosed |
| US-5552534-A | COMPOUNDS FOR CROSS REACTION WITH PEPTIDES FOR BINDING G PROTEIN | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1996-09-03 | — | — | US | disclosed |