Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19695817 | 0.88 | ALDH1A1 (0.54) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL7900537 | 0.85 | ALDH1A1 (0.48) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL9032101 | 0.80 | HRH2 (0.39) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL12695963 | 0.80 | PTPN1 (0.47) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL3686150 | 0.79 | ALDH1A1 (0.51) | HPGDALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14369503 | 0.78 | ALDH1A1 (0.58) | HPGDGAAALDH1A1MEN1KMT2A | |
| SCHEMBL15907989 | 0.76 | ALDH1A1 (0.48) | HPGDALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL13498680 | 0.76 | ALDH1A1 (0.46) | HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL10168511 | 0.76 | ALDH1A1 (0.47) | HPGDALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL8828394 | 0.76 | ALDH1A1 (0.45) | HPGDALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6217845-B1 | IMAGING; THERAPY | ANORMED, INC. (CA) | 2001-04-17 | — | — | US | disclosed |
| US-5206370-A | Certain pyridyl hydrazines and hydrazides useful for protein labeling | JOHNSON MATTHEY, INC. (US) | 1993-04-27 | — | — | US | disclosed |