Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 12/20 | 0.74 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.74 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.74 |
| ▸ | CHRM5 | P08912 | 7/20 | 0.74 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.74 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615579 | 0.93 | CHRM1 (0.70) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL7613589 | 0.93 | CHRM1 (0.74) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL7613448 | 0.92 | CHRM1 (0.68) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL7611132 | 0.91 | CHRM1 (0.74) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL7610906 | 0.91 | CHRM1 (0.74) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL4029522 | 0.88 | CHRM1 (0.67) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL7609678 | 0.87 | CHRM1 (0.69) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL7617382 | 0.86 | CHRM1 (0.71) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL7620716 | 0.85 | CHRM1 (0.78) | CHRM1CHRM2CHRM4CHRM5CHRM3 | |
| SCHEMBL7610514 | 0.85 | CHRM1 (0.70) | CHRM1CHRM2CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211204-B1 | THIADIAZOLE, HYDROGENATED PYRIDINE DERIVATIVES | UNIVERSITY OF TOLEDO | 2001-04-03 | — | — | US | disclosed |