Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791390 | 0.81 | CYP3A4 (0.32) | — | |
| SCHEMBL18619480 | 0.78 | APP (0.37) | APP | |
| SCHEMBL790036 | 0.71 | CSNK2A1 (0.41) | — | |
| SCHEMBL27937787 | 0.70 | APP (0.43) | APP | |
| SCHEMBL19230462 | 0.70 | NOS1 (0.41) | APP | |
| SCHEMBL9422180 | 0.70 | NOS1 (0.41) | APP | |
| SCHEMBL1297632 | 0.69 | NOS1 (0.44) | APP | |
| SCHEMBL29644321 | 0.69 | NOS1 (0.44) | APP | |
| SCHEMBL27937785 | 0.68 | EGFR (0.39) | APP | |
| SCHEMBL10713877 | 0.67 | NOS1 (0.42) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |