Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | PRNP | P04156 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824035 | 0.86 | TSHR (0.71) | TSHRKDM4EHPGDALDH1A1RXFP1 | |
| SCHEMBL2314666 | 0.86 | TSHR (0.56) | ADORA2ATSHRKDM4EHPGDALDH1A1 | |
| SCHEMBL10665205 | 0.85 | TSHR (0.58) | ADORA2ATSHRKDM4EHPGDALDH1A1 | |
| SCHEMBL5193947 | 0.82 | IKBKB (0.60) | TSHRKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL15124569 | 0.81 | ADORA2A (0.49) | ADORA2ATSHRKDM4EHPGDALDH1A1 | |
| SCHEMBL31228755 | 0.81 | ADORA2A (0.49) | ADORA2ATSHRKDM4EHPGDALDH1A1 | |
| SCHEMBL28087530 | 0.81 | TSHR (0.50) | ADORA2ATSHRKDM4EHPGDALDH1A1 | |
| SCHEMBL29077004 | 0.81 | KDM4E (0.57) | ADORA2ATSHRKDM4EHPGDALDH1A1 | |
| SCHEMBL790264 | 0.78 | PRNP (0.53) | ADORA2ATSHRKDM4EHPGDALDH1A1 | |
| SCHEMBL11548569 | 0.78 | IKBKB (0.63) | KDM4EHPGDALDH1A1PRNPRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |