Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.63 |
| ▸ | PRNP | P04156 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790264 | 0.87 | PRNP (0.53) | IKBKBPRNPKDM4EALDH1A1HPGD | |
| SCHEMBL790477 | 0.85 | PRNP (0.52) | IKBKBPRNPKDM4EALDH1A1HPGD | |
| Lithium SCHEMBL790479 | 0.85 | PRNP (0.52) | IKBKBPRNPKDM4EALDH1A1HPGD | |
| Lithium Ion SCHEMBL790478 | 0.84 | PRNP (0.51) | IKBKBPRNPKDM4EALDH1A1GLA | |
| SCHEMBL11549035 | 0.80 | IKBKB (0.63) | IKBKBKDM4EALDH1A1GLAGAA | |
| SCHEMBL790106 | 0.78 | ADORA2A (0.55) | PRNPKDM4EALDH1A1GAAHPGD | |
| SCHEMBL789573 | 0.78 | CDC7 (0.40) | IKBKBPRNPKDM4EALDH1A1GLA | |
| SCHEMBL11549068 | 0.78 | IKBKB (0.59) | IKBKBKDM4EALDH1A1GLAGAA | |
| SCHEMBL31060123 | 0.77 | IKBKB (1.00) | IKBKBKDM4EALDH1A1GLAGAA | |
| SCHEMBL30837 | 0.77 | IKBKB (1.00) | IKBKBKDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134981-A | ANTIALLERGENS | PFIZER INC. (US) | 1979-01-16 | — | — | US | disclosed |
| US-4120962-A | Fused pyrimidin-4(3H)-ones as antiallergy agents | PFIZER INC. (US) | 1978-10-17 | — | — | US | disclosed |
| US-4044134-A | FUSED WITH QUINOLINE OR PYRIDINE, 2-METHYL, ETHYL, OR ACETYL GROUP | PFIZER INC. (US) | 1977-08-23 | — | — | US | disclosed |
| US-3974161-A | Fused pyrimidin-4(3H)-ones as antiallergy agents | PFIZER INC. (US) | 1976-08-10 | — | — | US | disclosed |