Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL242750 | 1.00 | TSHR (0.69) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL242751 | 1.00 | TSHR (0.69) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL972676 | 1.00 | TSHR (0.69) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL9456765 | 0.98 | TSHR (0.67) | TSHRHCAR2CYP3A4TDP1ATM | |
| Hydrochloric Acid SCHEMBL4611985 | 0.98 | TSHR (0.67) | TSHRHCAR2CYP3A4TDP1ATM | |
| Hydrochloric Acid SCHEMBL4611981 | 0.98 | TSHR (0.67) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL9436436 | 0.98 | TSHR (0.67) | TSHRHCAR2CYP3A4TDP1ATM | |
| Ammonia Solution, Strong SCHEMBL9436306 | 0.98 | TSHR (0.67) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL9456754 | 0.98 | TSHR (0.67) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL6692852 | 0.98 | TSHR (0.67) | TSHRHCAR2CYP3A4TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035065-A2 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE VOLATILE LINEAR ALKANE WITH A FATTY ESTER OR ALCOHOL AND AT LEAST ONE PLANT OIL | L'OREAL (FR) | 2012-03-22 | — | — | WO | claimed |
| WO-2012055812-A1 | COSMETIC COMPOSITION COMPRISING A FATTY-CHAIN ALKOXYSILANE AND AN ANTIDANDRUFF AGENT. | L'OREAL (FR) | 2012-05-03 | — | — | WO | disclosed |