Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.50 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4611981 | 1.00 | TSHR (0.67) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL972676 | 0.98 | TSHR (0.69) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL242750 | 0.98 | TSHR (0.69) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL790118 | 0.98 | TSHR (0.69) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL242751 | 0.98 | TSHR (0.69) | TSHRHCAR2CYP3A4TDP1ATM | |
| Ammonia Solution, Strong SCHEMBL9436306 | 0.97 | TSHR (0.67) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL9456765 | 0.97 | TSHR (0.67) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL9456754 | 0.97 | TSHR (0.67) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL9436436 | 0.97 | TSHR (0.67) | TSHRHCAR2CYP3A4TDP1ATM | |
| SCHEMBL6692852 | 0.97 | TSHR (0.67) | TSHRHCAR2CYP3A4TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345074-B1 | Silver halide photographic light-sensitive material comprising a hydrocarbon and a fluorinated surfactant | FUJIFILM CORP (JP) | 2008-02-20 | — | — | EP | disclosed |
| US-7105285-B2 | Silver halide color photosensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2006-09-12 | — | — | US | disclosed |
| US-7005250-B2 | Silver halide color photographic lightsensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2006-02-28 | — | — | US | disclosed |
| US-6949670-B2 | Fluorocompound, silver halide photographic light-sensitive material, surfactant, and water-based coating composition employing same | FUJI PHOTO FILM CO., LTD. (JP) | 2005-09-27 | — | — | US | disclosed |
| US-20050118540-A1 | Image forming method | FUJI PHOTO FILM CO., LTD. | 2005-06-02 | — | — | US | disclosed |
| US-6897013-B2 | Silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2005-05-24 | — | — | US | disclosed |
| US-20050069824-A1 | Silver halide color photosensitive material | FUJI PHOTO FILM CO., LTD. | 2005-03-31 | — | — | US | disclosed |
| US-6872515-B2 | Silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2005-03-29 | — | — | US | disclosed |
| US-20050053872-A1 | Image forming method | FUJI PHOTO FILM CO., LTD. | 2005-03-10 | — | — | US | disclosed |
| US-6824964-B1 | BY INTRODUCING COLLOIDAL SILICA IN A REAR SURFACE SIDE (BACK LAYER) OF THE PHOTOSENSITIVE MATERIAL AND BY MAINTAINING SURFACE RESISTANCE ELIMINATES THE CHARGE CAUSED BY PEELING, THEREBY SUPPRESSING THE TRANSPORTING FAILURE | FUJI PHOTO FILM CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040137386-A1 | Silver halide color photographic lightsensitive material | FUJI PHOTO FILM CO., LTD. | 2004-07-15 | — | — | US | disclosed |
| US-20040048209-A1 | Antistatic property and shows reduced repellency during high speed coating, and can be stably produced | FUJI PHOTO FILM CO., LTD. | 2004-03-11 | — | — | US | disclosed |
| US-20040044244-A1 | Fluorocompound, silver halide photographic light-sensitive material, surfactant, and water-based coating composition empolying same | FUJI PHOTO FILM CO. LTD. | 2004-03-04 | — | — | US | disclosed |
| US-20040002024-A1 | Silver halide photographic light-sensitive material | FUJIFILM CORPORATION (JP) | 2004-01-01 | — | — | US | disclosed |
| EP-1345074-A1 | Silver halide photographic light-sensitive material comprising a hydrocarbon and a fluorinated surfactant | FUJI PHOTO FILM CO., LTD. (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6589723-B2 | Fluoroalkyl sulfosuccinates | FUJI FILM CO., LTD. (JP) | 2003-07-08 | — | — | US | disclosed |
| US-20020197571-A1 | Fluorocompound, silver halide photographic light-sensitive material, surfactant, and water-based coating composition employing same | FUJIFILM CORPORATION (JP) | 2002-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044244-A1 | Fluorocompound, silver halide photographic light-sensitive material, surfactant, and water-based coating composition empolying same | AFF1, MFAP1, AFF2 | CA2 4414/4885ACHE 2933/4885TSHR 2086/4885 |
| US-20020197571-A1 | Fluorocompound, silver halide photographic light-sensitive material, surfactant, and water-based coating composition employing same | AFF1, AFF2, MFAP1 | CA2 3813/4885ACHE 3227/4885TSHR 1082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.