Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 9/20 | 0.63 |
| ▸ | CXCR2 | P25025 | 11/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 2/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896676 | 0.84 | CXCR1 (0.57) | CXCR1CXCR2MEN1KMT2ATDP1 | |
| SCHEMBL5595168 | 0.84 | CXCR1 (0.69) | CXCR1CXCR2MEN1KMT2ATDP1 | |
| SCHEMBL5595211 | 0.83 | CXCR1 (0.64) | CXCR1CXCR2MEN1KMT2ATDP1 | |
| SCHEMBL7489633 | 0.82 | CXCR1 (0.66) | CXCR1CXCR2MEN1KMT2ATDP1 | |
| SCHEMBL5594648 | 0.79 | CXCR1 (0.66) | CXCR1CXCR2MEN1KMT2ATDP1 | |
| SCHEMBL5595020 | 0.78 | CXCR2 (0.68) | CXCR1CXCR2MEN1KMT2AHTT | |
| SCHEMBL7896679 | 0.78 | RAB9A (0.59) | CXCR1CXCR2MEN1KMT2ATDP1 | |
| SCHEMBL5595143 | 0.77 | CXCR1 (0.71) | CXCR1CXCR2MEN1KMT2ATDP1 | |
| SCHEMBL7490438 | 0.77 | CXCR1 (0.59) | CXCR1CXCR2MEN1KMT2ATDP1 | |
| SCHEMBL5595039 | 0.77 | CXCR1 (0.59) | CXCR1CXCR2MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180675-B1 | THERAPY FOR CHEMOKINE SENSITIVE DISEASE; USING A AROMATIC (THIO)UREA COMPOUND | SMITHKLINE BEECHAM CORPORATION | 2001-01-30 | — | — | US | disclosed |