Isothiocyanate

Isothiocyanate

SCHEMBL7901465

N=C=S.O=C(O)CC(O)(C(=O)O)C(Cc1ccccc1)C(=O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPD1 P10809 1/20 0.40
BLM P54132 1/20 0.40
HSPE1 P61604 1/20 0.40
CYP1A2 P05177 1/20 0.40
CPA3 P15088 3/20 0.40
CPA1 P15085 2/20 0.40
CPB1 P15086 1/20 0.40
CPB2 Q96IY4 1/20 0.40
CPT2 P23786 1/20 0.39
ACLY P53396 1/20 0.39
ALPI P09923 1/20 0.38
PKM P14618 1/20 0.38
PTGS1 P23219 1/20 0.38
XIAP P98170 1/20 0.38
SLC7A5 Q01650 1/20 0.38
SLC15A1 P46059 1/20 0.37
FOLH1 Q04609 1/20 0.36
SRR Q9GZT4 1/20 0.36
SLC1A3 P43003 1/20 0.36
SLC1A2 P43004 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28110561 0.90 CYP1A2 (0.46) HSPD1BLMHSPE1CYP1A2CPA3
SCHEMBL673675 0.77 CYP1A2 (0.48) CYP1A2CPA3CPA1CPB1CPB2
SCHEMBL304065 0.76 CYP1A2 (0.47) BLMCYP1A2CPA3CPA1CPB1
SCHEMBL306315 0.75 CYP1A2 (0.46) CYP1A2CPA3CPA1CPB1CPB2
SCHEMBL20394045 0.71 CYP1A2 (0.52) BLMCYP1A2CPA3CPA1CPB1
SCHEMBL28273509 0.69 KDM4E (0.42) HSPD1BLMHSPE1CYP1A2
Dl-Phenylalanine SCHEMBL26662794 0.69 SLC7A5 (0.79) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL28743400 0.68 CYP1A2 (0.57) CYP1A2CPA3CPA1CPB1CPB2
SCHEMBL11584543 0.68 ACLY (0.59) HSPD1BLMHSPE1CPT2ACLY
Isothiocyanate SCHEMBL7894347 0.67 CPT2 (0.46) HSPD1BLMHSPE1CPT2ACLY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6241961-B1 ADMINISTERING TO BONE MARROW OF PATIENT A DOSE OF A MONOCLONAL ANTIBODY OR ANTIBODY FRAGMENT STABLY COUPLED TO A CADMIUM-66 RADIOISOTOPE; SIDE EFFECT REDUCTION BENES IVAN FRIEDRICH (CH) 2001-06-05 US disclosed