Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | FYN | P06241 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CD74 | P04233 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7892524 | 0.85 | MAPT (0.49) | ALDH1A1L3MBTL1NPSR1MAPTFYN | |
| SCHEMBL7901561 | 0.78 | MAPT (0.39) | ALDH1A1L3MBTL1NPSR1MAPTFYN | |
| SCHEMBL9166097 | 0.76 | RAB9A (0.37) | ALDH1A1L3MBTL1NPSR1MAPTNPC1 | |
| SCHEMBL7436883 | 0.72 | MAPT (0.52) | ALDH1A1L3MBTL1MAPTFYNNPC1 | |
| SCHEMBL959394 | 0.70 | ABCB1 (0.44) | ALDH1A1L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL1219482 | 0.67 | KDM4E (0.49) | ALDH1A1L3MBTL1NPSR1MAPTFYN | |
| SCHEMBL956425 | 0.66 | KDM4E (0.39) | ALDH1A1L3MBTL1NPC1MEN1KMT2A | |
| SCHEMBL9168534 | 0.66 | MAPT (0.44) | ALDH1A1L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL9168017 | 0.65 | MAPT (0.39) | ALDH1A1L3MBTL1NPSR1MAPTNPC1 | |
| SCHEMBL7067985 | 0.65 | MAPT (0.74) | ALDH1A1NPSR1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197774-B1 | THERAPY FOR ASTHMA, SKIN DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |