Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.49 |
| ▸ | DPP4 | P27487 | 4/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744563 | 0.98 | LTA4H (0.50) | LTA4HDPP4HTR1DHTR1BTAAR1 | |
| SCHEMBL28985155 | 0.87 | TAAR1 (0.47) | LTA4HDPP4HTR1DHTR1BTAAR1 | |
| SCHEMBL14646142 | 0.87 | TAAR1 (0.36) | LTA4HHTR1DHTR1BTAAR1 | |
| SCHEMBL14646214 | 0.80 | HTR1D (0.30) | HTR1DHTR1BTAAR1 | |
| SCHEMBL9976549 | 0.80 | LTA4H (0.46) | LTA4HDPP4HTR1DHTR1BTAAR1 | |
| SCHEMBL14645333 | 0.80 | TAAR1 (0.35) | TAAR1 | |
| SCHEMBL9976551 | 0.78 | LTA4H (0.42) | LTA4HDPP4HTR1DHTR1BTAAR1 | |
| SCHEMBL9976572 | 0.75 | LTA4H (0.42) | LTA4HDPP4HTR1DHTR1BTAAR1 | |
| SCHEMBL17803944 | 0.74 | CYP1A2 (0.33) | — | |
| SCHEMBL26625918 | 0.74 | LTA4H (0.73) | LTA4HDPP4HTR1DHTR1BTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122291-A2 | Layered organic-inorganic perovskites having metal-deficient inorganic frameworks | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2001-08-08 | — | — | EP | claimed |