SCHEMBL7901644

SCHEMBL7901644

NP(O)OP

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL213695 0.70
SCHEMBL646321 0.67
SCHEMBL1500470 0.67
SCHEMBL12005226 0.67
SCHEMBL29125637 0.67
SCHEMBL29084440 0.67
SCHEMBL29099030 0.64
SCHEMBL7702462 0.64
SCHEMBL442336 0.64
SCHEMBL153732 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-217147140-U Phosphoramidite phosphorus reagent storage box 天津全和诚科技有限责任公司 2022-08-09 CN claimed
JP-10251281-A None JP disclosed
JP-10251281-A None JP disclosed
CN-116942841-A Targeting ligands 箭头药业股份有限公司 2023-10-27 CN disclosed
CN-116832169-A Targeting ligands 箭头药业股份有限公司 2023-10-03 CN disclosed
CN-109462981-B Targeting ligands 箭头药业股份有限公司 2023-07-07 CN disclosed
CN-217147140-U Phosphoramidite phosphorus reagent storage box 天津全和诚科技有限责任公司 2022-08-09 CN disclosed
CN-104725170-B Hydroformylation process 陶氏技术投资有限责任公司 2019-08-23 CN disclosed
CN-109983128-A Oligonucleotide composition and its method 波涛生命科学有限公司 2019-07-05 CN disclosed
EP-3500581-A1 POLYNUCLEOTIDE CONSTRUCTS Solstice Biologics, Ltd. (IE) 2019-06-26 EP disclosed
CN-104379258-A Hydroformylation process DOW TECHNOLOGY INVESTMENTS LLC 2015-02-25 CN disclosed
CN-103702758-A Method for storing transition metal organophosphorus ligand-based catalyst DOW TECHNOLOGY INVESTMENTS LLC 2014-04-02 CN disclosed
CN-103402961-A Mitigating fouling in hydroformylation processes by adding water DOW TECHNOLOGY INVESTMENTS LLC 2013-11-20 CN disclosed
US-6310198-B1 NUCLEOTIDE PHOSPHOROTHIOATES WITH LITTLE OR NO PHOSPHATE ESTER FOR USE AS ANTISENSE AGENTS; SULFURIZATION OF PROTECTED DINUCLEOTIDES AVECIA BIOTECHNOLOGY INC. 2001-10-30 US disclosed
US-6087491-A EFFICIENT PROCESS BY SYNTHESIZING OLIGONUCLEOTIDE WITH DIMER BLOCKS USING PHOSPHORAMIDITE CHEMISTRY AND SUBJECTING THE FULL-LENGTH, OLIGONUCLEOTIDE TO CHROMATOGRAPHY PURIFICATION; REDUCTION IN SOLVENT USE AND BY-PRODUCT PRODUCTION HYBRIDON, INC. (US) 2000-07-11 US disclosed
JP-H10251281-A PHOSPHOROUS ACID AMIDE PHOSPHINE F HOFFMANN LA ROCHE AG 1998-09-22 JP disclosed
JP-H10251281-A PHOSPHOROUS ACID AMIDE PHOSPHINE F HOFFMANN LA ROCHE AG 1998-09-22 JP disclosed
US-5721355-A Method of attaching a fluorescent label to an oligonucleotide PHARMACIA BIOTECH INC. (US) 1998-02-24 US disclosed
US-5583236-A PRIMERS FOR DNA SEQUENCING PHARMACIA BIOTECH INC. (US) 1996-12-10 US disclosed
US-5371241-A Fluorescein labelled phosphoramidites PHARMACIA P-L BIOCHEMICALS INC. (US) 1994-12-06 US disclosed