Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 8/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7892929 | 0.93 | CXCR3 (0.39) | CXCR3TAS1R3TAS1R1FFAR1SLC6A9 | |
| SCHEMBL7901816 | 0.88 | POLB (0.45) | KMT2ATAS1R3TAS1R1TRPM8GAA | |
| SCHEMBL6122200 | 0.81 | POLB (0.46) | KMT2ATAS1R3TAS1R1TRPM8GAA | |
| SCHEMBL17009347 | 0.81 | POLB (0.46) | KMT2ATAS1R3TAS1R1TRPM8GAA | |
| SCHEMBL6127110 | 0.81 | POLB (0.46) | KMT2ATAS1R3TAS1R1TRPM8GAA | |
| SCHEMBL6127212 | 0.81 | POLB (0.46) | KMT2ATAS1R3TAS1R1TRPM8GAA | |
| SCHEMBL4698443 | 0.81 | POLB (0.46) | KMT2ATAS1R3TAS1R1TRPM8GAA | |
| SCHEMBL20530282 | 0.81 | POLB (0.46) | KMT2ATAS1R3TAS1R1TRPM8GAA | |
| SCHEMBL7900077 | 0.79 | HPGD (0.44) | TAS1R3TAS1R1TRPM8GAAPOLB | |
| SCHEMBL4700500 | 0.78 | POLB (0.43) | KMT2ATAS1R3TAS1R1TRPM8HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194448-B1 | ANTIINFLAMMATORY AGENTS; ASTHMA; RHEUMATIC DISORDERS | TEXAS BIOTECHNOLOGY CORPORATION | 2001-02-27 | — | — | US | disclosed |