Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 2/20 | 0.46 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.46 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 4/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13381041 | 1.00 | SSTR5 (0.46) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL3156185 | 1.00 | SSTR5 (0.46) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL13381054 | 0.97 | SSTR5 (0.45) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL6761890 | 0.95 | SSTR5 (0.45) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL13380946 | 0.94 | SSTR5 (0.42) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL6886072 | 0.92 | SSTR5 (0.46) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7906067 | 0.90 | SSTR1 (0.56) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7906068 | 0.90 | SSTR1 (0.56) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL3156190 | 0.90 | SSTR1 (0.53) | SSTR5SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL24996978 | 0.89 | SSTR5 (0.47) | SSTR5SSTR1SSTR2SSTR4SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197963-B1 | TETRAHYDROPYRAN DERIVATIVES; PROTEIN G, SOMATOSTATIN, AND NATURAL KILLER CELL RECEPTOR ANTAGONISTS OR MIMETICS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2001-03-06 | — | — | US | disclosed |
| US-5811512-A | BINDING TO G-PROTEIN-LINKED RECEPTORS, SUBSTANCE P RECEPTOR; HORMONE INHIBITORS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-09-22 | — | — | US | disclosed |
| US-5552534-A | COMPOUNDS FOR CROSS REACTION WITH PEPTIDES FOR BINDING G PROTEIN | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1996-09-03 | — | — | US | disclosed |