SCHEMBL13380946

SCHEMBL13380946

COc1ccc(COC2[C@@H](OC)OC(CO[Si](c3ccccc3)(c3ccccc3)C(C)(C)C)[C@@H](O)[C@H]2OCc2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SSTR5 P35346 5/20 0.42
SSTR1 P30872 1/20 0.42
SSTR2 P30874 1/20 0.42
SSTR4 P31391 1/20 0.42
SSTR3 P32745 1/20 0.42
BCHE P06276 1/20 0.38
PTPN1 P18031 9/20 0.38
PTPN2 P17706 6/20 0.38
CDC25B P30305 6/20 0.38
CDC25A P30304 2/20 0.38
LGALS8 O00214 1/20 0.38
GJB2 P29033 1/20 0.37
GJA1 P17302 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13381041 0.94 SSTR5 (0.46) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL7902126 0.94 SSTR5 (0.46) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL3156185 0.94 SSTR5 (0.46) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL13381054 0.91 SSTR5 (0.45) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL14221752 0.90 SSTR5 (0.39) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL6761890 0.90 SSTR5 (0.45) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL13380992 0.90 SSTR5 (0.39) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL6886072 0.86 SSTR5 (0.46) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL6951099 0.85 SSTR5 (0.54) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL7906067 0.85 SSTR1 (0.56) SSTR5SSTR1SSTR2SSTR4SSTR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100081708-A1 ANTICOAGULANT COMPOUNDS ENDOTIS PHARMA (FR) 2010-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100081708-A1 ANTICOAGULANT COMPOUNDS SERPINC1, F2, FUT5 SSTR5 1014/4885SSTR1 1801/4885SSTR2 1551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.