Trifluoroacetic Acid

SCHEMBL7902234

COC(=O)C(Cc1cccc(C(=N)N)c1)C(C)NC(=O)c1ccc(-c2ccc(=O)[nH]c2)cc1.O=C(O)C(F)(F)F

nearest known ligand 0.73

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	F10	P00742	20/20	0.73

▸	PRSS1	P07477	18/20	0.73

▸	F2	P00734	6/20	0.73

▸	PLG	P00747	1/20	0.70

▸	TMPRSS2	O15393	1/20	0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Trifluoroacetic Acid SCHEMBL6641247	1.00	F10 (0.73)	F10PRSS1F2PLGTMPRSS2
Trifluoroacetic Acid SCHEMBL6638262	0.86	F10 (0.76)	F10PRSS1F2PLGTMPRSS2
Trifluoroacetic Acid SCHEMBL6638259	0.86	F10 (0.76)	F10PRSS1F2PLGTMPRSS2
Trifluoroacetic Acid SCHEMBL6644529	0.83	F10 (0.73)	F10PRSS1F2PLGTMPRSS2
Trifluoroacetic Acid SCHEMBL6644526	0.83	F10 (0.73)	F10PRSS1F2PLGTMPRSS2
Hydrochloric Acid SCHEMBL6640617	0.83	F10 (0.78)	F10PRSS1F2PLGTMPRSS2
Trifluoroacetic Acid SCHEMBL6680558	0.82	F10 (0.89)	F10PRSS1F2PLGTMPRSS2
SCHEMBL7898536	0.81	F10 (0.57)	F10PRSS1F2PLGTMPRSS2
SCHEMBL6639955	0.81	F10 (0.57)	F10PRSS1F2PLGTMPRSS2
SCHEMBL12589582	0.81	F10 (1.00)	F10PRSS1F2PLGTMPRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6323227-B1	PRODRUGS	AVENTIS PHARMACEUTICALS PRODUCTS INC.	2001-11-27	—	—	US	claimed
US-6323227-B1	PRODRUGS	AVENTIS PHARMACEUTICALS PRODUCTS INC.	2001-11-27	—	—	US	disclosed