Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 17/20 | 0.57 |
| ▸ | F2 | P00734 | 5/20 | 0.57 |
| ▸ | PLG | P00747 | 1/20 | 0.57 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6639955 | 1.00 | F10 (0.57) | F10PRSS1F2PLGTMPRSS2 | |
| Trifluoroacetic Acid SCHEMBL6641247 | 0.81 | F10 (0.73) | F10PRSS1F2PLGTMPRSS2 | |
| Trifluoroacetic Acid SCHEMBL7902234 | 0.81 | F10 (0.73) | F10PRSS1F2PLGTMPRSS2 | |
| Hydrochloric Acid SCHEMBL6640617 | 0.74 | F10 (0.78) | F10PRSS1F2PLGTMPRSS2 | |
| SCHEMBL13636886 | 0.74 | F10 (0.74) | F10PRSS1F2PLG | |
| SCHEMBL6638366 | 0.74 | F10 (0.55) | F10PRSS1F2PLGTMPRSS2 | |
| SCHEMBL6638363 | 0.74 | F10 (0.55) | F10PRSS1F2PLGTMPRSS2 | |
| SCHEMBL12589582 | 0.71 | F10 (1.00) | F10PRSS1F2PLGTMPRSS2 | |
| SCHEMBL12521569 | 0.71 | F10 (1.00) | F10PRSS1F2PLGTMPRSS2 | |
| SCHEMBL10072203 | 0.71 | F10 (1.00) | F10PRSS1F2PLGTMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323227-B1 | PRODRUGS | AVENTIS PHARMACEUTICALS PRODUCTS INC. | 2001-11-27 | — | — | US | claimed |
| US-6323227-B1 | PRODRUGS | AVENTIS PHARMACEUTICALS PRODUCTS INC. | 2001-11-27 | — | — | US | disclosed |