Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.37 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.37 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.37 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14440928 | 0.89 | ALDH1A1 (0.43) | L3MBTL1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL14428933 | 0.89 | ALDH1A1 (0.43) | L3MBTL1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL14568965 | 0.89 | ALDH1A1 (0.43) | L3MBTL1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL14440540 | 0.89 | ALDH1A1 (0.43) | L3MBTL1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL7902115 | 0.83 | TSHR (0.34) | L3MBTL1KMT2AMEN1ALDH1A1GAA | |
| SCHEMBL17773534 | 0.83 | PTGES2 (0.41) | ALDH1A1GAAABCB1TSHRBCHE | |
| SCHEMBL7932128 | 0.81 | ALDH1A1 (0.38) | L3MBTL1KMT2AALDH1A1GAAABCB1 | |
| SCHEMBL4945560 | 0.79 | KMT2A (0.68) | L3MBTL1KMT2AMEN1ALDH1A1LGALS3 | |
| SCHEMBL7152880 | 0.79 | KMT2A (0.68) | L3MBTL1KMT2AMEN1ALDH1A1LGALS3 | |
| SCHEMBL19186152 | 0.79 | KMT2A (0.68) | L3MBTL1KMT2AMEN1ALDH1A1LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197963-B1 | TETRAHYDROPYRAN DERIVATIVES; PROTEIN G, SOMATOSTATIN, AND NATURAL KILLER CELL RECEPTOR ANTAGONISTS OR MIMETICS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2001-03-06 | — | — | US | disclosed |
| US-5811512-A | BINDING TO G-PROTEIN-LINKED RECEPTORS, SUBSTANCE P RECEPTOR; HORMONE INHIBITORS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-09-22 | — | — | US | disclosed |
| WO-1993017032-A1 | TECHNIQUES AND INTERMEDIATES FOR PREPARING NON-PEPTIDE PEPTIDOMIMETICS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1993-09-02 | — | — | WO | disclosed |