Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorsulfuron SCHEMBL54874 | 1.00 | ALDH1A1 (0.61) | ALDH1A1KDM4ENPC1CA12CA1 | |
| Chlorsulfuron SCHEMBL29636275 | 1.00 | ALDH1A1 (0.61) | ALDH1A1KDM4ENPC1CA12CA1 | |
| Chlorsulfuron SCHEMBL11325389 | 1.00 | ALDH1A1 (0.61) | ALDH1A1KDM4ENPC1CA12CA1 | |
| Chlorsulfuron SCHEMBL28654480 | 0.99 | ALDH1A1 (0.60) | ALDH1A1KDM4ENPC1CA12CA1 | |
| SCHEMBL11636558 | 0.93 | ALDH1A1 (0.66) | ALDH1A1KDM4ENPC1CA12CA1 | |
| Chlorsulfuron SCHEMBL3428108 | 0.93 | ALDH1A1 (0.55) | ALDH1A1KDM4ENPC1CA12CA1 | |
| Chlorsulfuron SCHEMBL9721408 | 0.90 | ALDH1A1 (0.52) | ALDH1A1KDM4ENPC1CA12CA1 | |
| SCHEMBL11637640 | 0.89 | KDM4E (0.60) | ALDH1A1KDM4ENPC1CA12CA1 | |
| SCHEMBL11040368 | 0.89 | ALDH1A1 (0.50) | ALDH1A1KDM4ENPC1CA12CA1 | |
| SCHEMBL10964766 | 0.89 | KDM4E (0.49) | ALDH1A1KDM4ENPC1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6222100-B1 | CULTIVATING A MONOCOTYLEDONOUS PLANT WHICH IS RESISTANT TO 2-(2-IMIDAZOLIN-2-YL)PYRIDINE HERBICIDE OR DERIVATIVE BECAUSE OF ALTERED ACETOHYDROXYACID SYNTHASE | MGI PHARMA, INC. | 2001-04-24 | — | — | US | disclosed |
| US-6211439-B1 | FOR CROPS WHICH ARE RESISTANT TO HERBICIDES, AND WHICH GENETICALLY TRANSMIT THIS CHARACTERISTIC TO THEIR PROGENY | MGI PHARMA, INC | 2001-04-03 | — | — | US | disclosed |
| US-6211438-B1 | FOR CROPS WHICH ARE RESISTANT TO HERBICIDES, AND WHICH GENETICALLY TRANSMIT THIS CHARACTERISTIC TO THEIR PROGENY | MGI PHARMA, INC. | 2001-04-03 | — | — | US | disclosed |
| EP-0574418-B1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5463081-A | Chemical intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| US-5331107-A | Synthetase | MGI PHARMA, INC. (US) | 1994-07-19 | — | — | US | disclosed |
| US-5304732-A | Maize seeds, plants | MGI PHARMA, INC. (US) | 1994-04-19 | — | — | US | disclosed |
| EP-0154204-B1 | Herbicide resistance in plants | MGI PHARMA INC (US) | 1994-01-12 | — | — | EP | disclosed |
| WO-1992022203-A1 | SUBSTITUTED PYRIDINE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |
| WO-1992004827-A1 | HERBICIDAL SUBSTITUTED BICYCLIC TRIAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-02 | — | — | WO | disclosed |
| US-4761373-A | ACETOHYDROXYACID SYNTHASE ENZYME | MOLECULAR GENETICS, INC. (US) | 1988-08-02 | — | — | US | disclosed |