Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19186660 | 1.00 | DPP4 (0.48) | DPP4DPP7ALDH1A1MAPTHTT | |
| SCHEMBL902826 | 0.87 | DPP4 (0.48) | DPP4DPP7ALDH1A1MAPTHTT | |
| SCHEMBL3721167 | 0.87 | DPP4 (0.48) | DPP4DPP7ALDH1A1MAPTHTT | |
| SCHEMBL3719922 | 0.87 | DPP4 (0.48) | DPP4DPP7ALDH1A1MAPTHTT | |
| SCHEMBL25663616 | 0.83 | DPP4 (0.47) | DPP4DPP7 | |
| SCHEMBL8238467 | 0.83 | DPP4 (0.44) | DPP4DPP7ALDH1A1MAPTHTT | |
| SCHEMBL743991 | 0.83 | DPP4 (0.53) | DPP4DPP7 | |
| SCHEMBL3721356 | 0.83 | DPP4 (0.47) | DPP4DPP7ALDH1A1MAPTHTT | |
| SCHEMBL571909 | 0.83 | DPP4 (0.53) | DPP4DPP7 | |
| SCHEMBL743042 | 0.83 | DPP4 (0.53) | DPP4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122578-A2 | PROCESS FOR THE PREPARATION OF SITAGLIPTIN AND ITS INTERMEDIATES | MSN LABORATORIES LIMITED (IN) | 2010-10-28 | — | — | WO | disclosed |