Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 3/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.47 |
| ▸ | GSK3B | P49841 | 3/20 | 0.47 |
| ▸ | CDK4 | P11802 | 3/20 | 0.47 |
| ▸ | CCND1 | P24385 | 3/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.44 |
| ▸ | PRKCA | P17252 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | PRKCB | P05771 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942368 | 0.82 | PARP1 (0.47) | CDK5CDK5R1GSK3BCDK4CCND1 | |
| SCHEMBL11711039 | 0.82 | DAO (0.47) | CDK5CDK5R1GSK3BCDK4CCND1 | |
| SCHEMBL5334328 | 0.82 | CDK4 (0.44) | CDK5CDK5R1GSK3BCDK4CCND1 | |
| SCHEMBL549156 | 0.82 | CDK4 (0.57) | CDK5CDK5R1GSK3BCDK4CCND1 | |
| SCHEMBL11757345 | 0.80 | PADI4 (0.56) | CDK5CDK5R1GSK3BCDK4CCND1 | |
| SCHEMBL17604435 | 0.78 | CDK5 (0.41) | CDK5CDK5R1GSK3BCDK4CCND1 | |
| SCHEMBL11903054 | 0.75 | CDK4 (0.55) | CDK5CDK5R1GSK3BCDK4CCND1 | |
| SCHEMBL11713467 | 0.75 | KDM4E (0.55) | CDK5CDK5R1GSK3BCDK4CCND1 | |
| SCHEMBL18068454 | 0.74 | KDM4E (0.46) | SERPINE1EGFRMAPTMEN1KMT2A | |
| SCHEMBL28430382 | 0.74 | GSK3B (0.36) | GSK3BGSK3APRKCAEGFRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108727264-B | Preparation method of naphthalimide diester fluorescent dye and composition thereof | 斯佩特罗尼克斯公司 | 2022-04-26 | — | — | CN | claimed |
| US-9845390-B1 | Process for producing naphthalimide diester fluorescent dyes and compositions thereof | SPECTRONICS CORPORATION (US) | 2017-12-19 | — | — | US | claimed |
| US-6248890-B1 | REACTING A NAPHTHALIMIDE DIOL WITH A FATTY ACID HAVING FROM 8 TO 24 CARBON ATOMS | DAY-GLO COLOR CORP. | 2001-06-19 | — | — | US | claimed |
| CN-108727264-B | Preparation method of naphthalimide diester fluorescent dye and composition thereof | 斯佩特罗尼克斯公司 | 2022-04-26 | — | — | CN | disclosed |
| US-9845390-B1 | Process for producing naphthalimide diester fluorescent dyes and compositions thereof | SPECTRONICS CORPORATION (US) | 2017-12-19 | — | — | US | disclosed |
| US-6248890-B1 | REACTING A NAPHTHALIMIDE DIOL WITH A FATTY ACID HAVING FROM 8 TO 24 CARBON ATOMS | DAY-GLO COLOR CORP. | 2001-06-19 | — | — | US | disclosed |