Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.44 |
| ▸ | CCND1 | P24385 | 4/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.44 |
| ▸ | GSK3A | P49840 | 3/20 | 0.44 |
| ▸ | GSK3B | P49841 | 3/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.44 |
| ▸ | PRKCA | P17252 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.40 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.40 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902933 | 0.82 | CDK5 (0.47) | CDK4CCND1CDK5CDK5R1GSK3A | |
| SCHEMBL10942368 | 0.78 | PARP1 (0.47) | CDK4CCND1CDK5CDK5R1GSK3A | |
| SCHEMBL9040639 | 0.77 | ALDH1A1 (0.40) | GSK3AGSK3BPRKCAEGFRMEN1 | |
| SCHEMBL549156 | 0.77 | CDK4 (0.57) | CDK4CCND1CDK5CDK5R1GSK3A | |
| SCHEMBL11757345 | 0.75 | PADI4 (0.56) | CDK4CCND1CDK5CDK5R1GSK3A | |
| SCHEMBL11711039 | 0.74 | DAO (0.47) | CDK4CCND1CDK5CDK5R1GSK3A | |
| SCHEMBL17604435 | 0.74 | CDK5 (0.41) | CDK4CCND1CDK5CDK5R1GSK3A | |
| SCHEMBL9621908 | 0.72 | MEN1 (0.46) | SERPINE1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL11903054 | 0.71 | CDK4 (0.55) | CDK4CCND1CDK5CDK5R1GSK3A | |
| SCHEMBL11713467 | 0.70 | KDM4E (0.55) | CDK4CCND1CDK5CDK5R1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058630-A1 | NOVEL BIS(AMINO)-ORTHO-DICARBABORANE CLUSTER COMPOUNDS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2007-05-24 | — | — | WO | disclosed |