Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18616795 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL12082379 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL7904241 | 0.82 | HTR2A (0.47) | ALDH1A1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL12546659 | 0.81 | KDM4E (0.42) | ALDH1A1KDM4EHPGDLMNAPARP1 | |
| SCHEMBL17141740 | 0.81 | MEN1 (0.42) | ALDH1A1KMT2AKDM4EHPGDLMNA | |
| SCHEMBL29956886 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KMT2AKDM4EHPGDLMNA | |
| SCHEMBL7903315 | 0.81 | HTR2A (0.41) | ALDH1A1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL21335645 | 0.80 | KDM4E (0.41) | ALDH1A1KMT2AHTR2AHTR2CHTR2B | |
| SCHEMBL12545657 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KMT2AKDM4EHPGDLMNA | |
| SCHEMBL8242914 | 0.77 | KDM4E (0.64) | ALDH1A1KMT2AKDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |