Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5803358 | 0.85 | HPGD (0.49) | RAB9AGAAHPGDDRD2DRD4 | |
| SCHEMBL31488089 | 0.83 | NPC1 (0.51) | RAB9AALDH1A1KDM4EDRD2DRD4 | |
| SCHEMBL880654 | 0.83 | NPC1 (0.51) | RAB9AALDH1A1KDM4EDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL853073 | 0.82 | NPC1 (0.50) | RAB9AALDH1A1KDM4EDRD2DRD4 | |
| SCHEMBL27370339 | 0.81 | NPC1 (0.64) | RAB9APOLBGAAALDH1A1KDM4E | |
| SCHEMBL30718462 | 0.81 | NPC1 (0.64) | RAB9APOLBGAAALDH1A1KDM4E | |
| SCHEMBL6421787 | 0.81 | RAB9A (0.52) | RAB9AGAAALDH1A1KDM4EHPGD | |
| SCHEMBL29642942 | 0.80 | PLAU (0.52) | ALDH1A1KDM4EDRD2DRD4MAPT | |
| SCHEMBL11411975 | 0.80 | RAB9A (0.55) | RAB9ACYP3A4POLBGAAALDH1A1 | |
| SCHEMBL8515392 | 0.79 | KMT2A (0.57) | RAB9AGAAALDH1A1KDM4EDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |