Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31495992 | 0.88 | ELANE (0.70) | ELANE | |
| SCHEMBL4022133 | 0.88 | ELANE (0.70) | ELANE | |
| SCHEMBL4126035 | 0.84 | ELANE (0.74) | ELANE | |
| SCHEMBL4134848 | 0.81 | ELANE (0.70) | ELANE | |
| Alvelestat SCHEMBL30179302 | 0.80 | ELANE (1.00) | ELANE | |
| Alvelestat SCHEMBL29519811 | 0.80 | ELANE (1.00) | ELANE | |
| Alvelestat SCHEMBL560757 | 0.80 | ELANE (1.00) | ELANE | |
| Alvelestat SCHEMBL29740084 | 0.80 | ELANE (1.00) | ELANE | |
| SCHEMBL7910137 | 0.79 | NOTUM (0.51) | ELANE | |
| SCHEMBL23925515 | 0.78 | ELANE (0.72) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094964-A1 | TOSYLATE SALT OF A 5-PYRAZOLYL-2-PYRIDONE DERIVATIVE, USEFUL IN THE TREATMENT OF COPD | ASTRAZENECA AB (SE) | 2010-08-26 | — | — | WO | disclosed |