Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 12/20 | 0.56 |
| ▸ | PI4KA | P42356 | 10/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791562 | 0.89 | PIK3CG (0.57) | PIK3CGPI4KAPIK3CDPIK3CAPIK3CB | |
| SCHEMBL796868 | 0.89 | PIK3CG (0.60) | PIK3CGPI4KAPIK3CDPIK3CAPIK3CB | |
| SCHEMBL10274844 | 0.87 | PIK3CG (0.54) | PIK3CGPI4KAPIK3CDPIK3CAPIK3CB | |
| SCHEMBL790922 | 0.87 | PI4KA (0.60) | PIK3CGPI4KAPIK3CDPIK3CARIPK2 | |
| SCHEMBL806962 | 0.86 | PI4KA (0.62) | PIK3CGPI4KAPIK3CDPIK3CAPIK3CB | |
| SCHEMBL807197 | 0.86 | PIK3CG (0.59) | PIK3CGPI4KAPIK3CDPIK3CAPIK3CB | |
| SCHEMBL791172 | 0.86 | PI4KA (0.68) | PIK3CGPI4KAPIK3CDPIK3CA | |
| SCHEMBL790025 | 0.85 | PIK3CG (0.56) | PIK3CGPI4KAPIK3CDPIK3CAPIK3CB | |
| SCHEMBL10274684 | 0.85 | PIK3CG (0.60) | PIK3CGPI4KAPIK3CDPIK3CAPIK3CB | |
| SCHEMBL789858 | 0.84 | PI4KA (0.59) | PIK3CGPI4KAPIK3CDPIK3CARIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |