Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 7/20 | 0.67 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.67 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.54 |
| ▸ | MTOR | P42345 | 4/20 | 0.54 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807215 | 0.97 | PIK3CG (0.69) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL807097 | 0.94 | PIK3CG (0.70) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL791014 | 0.90 | PIK3CG (0.73) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL10274859 | 0.89 | PIK3CG (0.71) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL10274761 | 0.88 | PIK3CG (0.75) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL807406 | 0.87 | PIK3CG (0.69) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL807104 | 0.87 | PIK3CG (0.69) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL790435 | 0.87 | PIK3CG (0.73) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL807107 | 0.85 | PIK3CG (0.70) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL789499 | 0.84 | PIK3CG (0.65) | PI4KAPIK3CGPIK3CAMTORPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |