Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 9/20 | 0.69 |
| ▸ | PI4KA | P42356 | 7/20 | 0.69 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | MTOR | P42345 | 6/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.52 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791014 | 0.90 | PIK3CG (0.73) | PIK3CGPI4KAPIK3CAHDAC1MTOR | |
| SCHEMBL10274859 | 0.89 | PIK3CG (0.71) | PIK3CGPI4KAPIK3CAHDAC1MTOR | |
| SCHEMBL10274761 | 0.88 | PIK3CG (0.75) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL807215 | 0.88 | PIK3CG (0.69) | PIK3CGPI4KAPIK3CAHDAC1MTOR | |
| SCHEMBL807106 | 0.87 | PIK3CG (0.76) | PIK3CGPI4KAPIK3CAHDAC1MTOR | |
| SCHEMBL790320 | 0.87 | PI4KA (0.67) | PIK3CGPI4KAPIK3CAHDAC1MTOR | |
| SCHEMBL807107 | 0.86 | PIK3CG (0.70) | PIK3CGPI4KAPIK3CAHDAC1MTOR | |
| SCHEMBL807104 | 0.84 | PIK3CG (0.69) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL790639 | 0.84 | PIK3CG (0.73) | PIK3CGPI4KAPIK3CAHDAC1MTOR | |
| SCHEMBL789313 | 0.83 | PIK3CG (0.76) | PIK3CGPI4KAPIK3CAHDAC1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |