SCHEMBL7903237

SCHEMBL7903237

Nc1ccc(OCc2ccc(Cl)cc2)cc1F

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOB P27338 13/20 0.59
MAOA P21397 6/20 0.59
APP P05067 1/20 0.51
DHFR P00374 1/20 0.49
TEC P42680 1/20 0.47
NR4A2 P43354 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3505720 0.87 MAOB (0.64) MAOBMAOAAPPNR4A2
SCHEMBL30792435 0.85 MAOB (0.54) MAOBMAOA
SCHEMBL5087372 0.85 MAOB (0.61) MAOBMAOAAPPDHFRTEC
SCHEMBL519206 0.83 MAOB (0.58) MAOBMAOA
Hydrochloric Acid SCHEMBL4716320 0.82 MAOB (0.56) MAOBMAOA
SCHEMBL7677809 0.82 NPC1 (0.48) MAOBMAOA
SCHEMBL4334933 0.81 MAOB (0.65) MAOBMAOA
SCHEMBL13577134 0.80 MAOB (0.59) MAOBMAOAAPPDHFRTEC
SCHEMBL30885393 0.78 PTPRZ1 (0.68) MAOBMAOA
SCHEMBL30792359 0.77 CCR5 (0.46) MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6200935-B1 FOR CONTROLLING UNDESIRABLE PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2001-03-13 US disclosed
EP-0968195-A1 ARYLALKYLTRIAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES Bayer Aktiengesellschaft (DE) 2000-01-05 EP disclosed
WO-1999001440-A1 SUBSTITUTED ARYLURACIL HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1999-01-14 WO disclosed
WO-1998032745-A1 ARYLALKYLTRIAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-07-30 WO disclosed
WO-1995017096-A1 HERBICIDAL HALOALKYLURACILS FMC CORPORATION (US) 1995-06-29 WO disclosed
US-5399543-A Chemical intermediates for the herbicides also claimed. FMC CORPORATION (US) 1995-03-21 US disclosed