Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CCR4 | P51679 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5101331 | 0.87 | HTR2A (0.58) | HTR2AL3MBTL1HSD17B10CYP1A2CYP2C19 | |
| SCHEMBL4109207 | 0.86 | ABCB1 (0.43) | HTR2AL3MBTL1CYP1A2CYP2C19HTR1B | |
| SCHEMBL17013852 | 0.85 | HTR2A (0.47) | HTR2AL3MBTL1HSD17B10CYP1A2CYP2C19 | |
| SCHEMBL14543901 | 0.82 | ABCB1 (0.45) | HTR2AL3MBTL1CYP1A2CYP2C19CYP2D6 | |
| Hydrochloric Acid SCHEMBL3292392 | 0.80 | ABCB1 (0.44) | HTR2AL3MBTL1CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL713198 | 0.79 | HTR2A (0.54) | HTR2AL3MBTL1HSD17B10CYP1A2CYP2C19 | |
| SCHEMBL29494584 | 0.79 | HTR2A (0.54) | HTR2AL3MBTL1HSD17B10CYP1A2CYP2C19 | |
| SCHEMBL15471003 | 0.79 | SMN1; SMN2 (0.49) | CYP1A2CYP2C19CYP2D6KMT2AMEN1 | |
| SCHEMBL11627125 | 0.78 | CYP1A2 (0.65) | HTR2AL3MBTL1HSD17B10CYP1A2CYP2C19 | |
| SCHEMBL5854479 | 0.78 | HTR2A (0.48) | HTR2AL3MBTL1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2018-08-02 | — | — | US | disclosed |
| EP-1068216-A2 | LIBRARIES OF OLIGOMERS LABELLED WITH DIFFERENT TAGS | ISIS INNOVATION LIMITED (GB) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999060007-A2 | LIBRARIES OF OLIGOMERS LABELLED WITH DIFFERENT TAGS | ISIS INNOVATION LIMITED (GB) | 1999-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | MRPL38, CXCL8, ALG8 | HTR2A 4461/4885L3MBTL1 744/4885HSD17B10 759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.