Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.53 |
| ▸ | TACR1 | P25103 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911462 | 1.00 | RORC (0.53) | RORCTACR1BCHEACHEBACE1 | |
| SCHEMBL3014338 | 1.00 | RORC (0.53) | RORCTACR1BCHEACHEBACE1 | |
| SCHEMBL3011761 | 1.00 | RORC (0.53) | RORCTACR1BCHEACHEBACE1 | |
| SCHEMBL3008068 | 1.00 | RORC (0.53) | RORCTACR1BCHEACHEBACE1 | |
| SCHEMBL3712743 | 1.00 | RORC (0.53) | RORCTACR1BCHEACHEBACE1 | |
| SCHEMBL3003822 | 1.00 | RORC (0.53) | RORCTACR1BCHEACHEBACE1 | |
| SCHEMBL3007011 | 1.00 | RORC (0.53) | RORCTACR1BCHEACHEBACE1 | |
| SCHEMBL3007007 | 1.00 | RORC (0.53) | RORCTACR1BCHEACHEBACE1 | |
| SCHEMBL14641855 | 1.00 | RORC (0.53) | RORCTACR1BCHEACHEBACE1 | |
| SCHEMBL13209035 | 0.90 | RORC (0.52) | RORCBCHEACHEBACE1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086259-A1 | PIPERIDINE DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-08-05 | — | — | WO | disclosed |