Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTSK | P43235 | 3/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 4/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904098 | 1.00 | CTSS (0.53) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL28054107 | 0.89 | CTSS (0.53) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL12122453 | 0.89 | CTSS (0.64) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL1273042 | 0.89 | CTSS (0.64) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL3725005 | 0.87 | ACE (0.59) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL3725007 | 0.87 | ACE (0.59) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL85543 | 0.86 | CTSS (0.64) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL22404737 | 0.86 | CTSS (0.64) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL3355326 | 0.86 | CTSS (0.64) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL3723164 | 0.86 | BCL2 (0.62) | CTSSCTSKCTSLCTSBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197794-B1 | ANTIINFLAMAMTORY AGENTS; IMMUNOLOGY DISEASES | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-03-06 | — | — | US | disclosed |