SCHEMBL7904155

SCHEMBL7904155

C[C@H](NC(=O)CC(C)(C)C)C(=O)NCCC(=O)OCCOc1ccc(-c2c(C#N)c(SCc3csc(-c4ccc(Cl)cc4)n3)nc(N3CCCC3)c2C#N)cc1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 20/20 0.50
SLC6A3 Q01959 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15679132 0.93 ADORA1 (0.53) ADORA1SLC6A3
SCHEMBL13227751 0.92 ADORA1 (0.50) ADORA1SLC6A3
SCHEMBL7894342 0.90 ADORA1 (0.56) ADORA1SLC6A3
SCHEMBL13227774 0.87 ADORA1 (0.54) ADORA1SLC6A3
Trifluoroacetic Acid SCHEMBL3731258 0.87 ADORA1 (0.52) ADORA1SLC6A3
SCHEMBL21134504 0.87 ADORA1 (0.52) ADORA1SLC6A3
SCHEMBL3728713 0.87 ADORA1 (0.50) ADORA1SLC6A3
SCHEMBL3733392 0.86 ADORA1 (0.54) ADORA1SLC6A3
SCHEMBL3734460 0.86 ADORA1 (0.50) ADORA1SLC6A3
SCHEMBL7894255 0.85 ADORA1 (0.56) ADORA1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010086101-A1 ALKYLAMINE-SUBSTITUTED DICYANOPYRIDINE AND AMINO ACID ESTER PRODRUGS THEREOF BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2010-08-05 WO disclosed